Perfusion index as a predictor for optimum positive end -expiratory pressure in Acute Respiratory Distress Syndrome patients management

Perfusion index as a predictor for optimum positive end-expiratory pressure(PEEP) in acute respiratory distress syndrome(ARDS) patients management

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000638639

Acronym

Pip ops

Enrollment

Registered

2014-06-17

Start date

2014-05-05

Completion date

2024-06-05

Last updated

2024-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We will study the relation between perfusion index and optimum positive end expiratory pressure in Acute respiratory distress syndrome patients management.

Interventions

We will titrate the PEEP level from baseline(5cm.H2O) by increments of 2cm.H2O for 30 minutes for each PEEP level till reaching the value of optimum PEEP that corresponds to best oxygenation(Pao2-sao2 and hypoxic index ) and correlates it with the perfusion index changes in ARDS patients.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

ARDS patients due to pulmonary causes (eg severe pneumonia).

Exclusion criteria

Extra pulmonary causes of ARDS, pneumothorax, coagulapathy CHF , cardiogenic pulmonary edema, hemodynamics instability.

Outcome results