None listed
Conditions
Brief summary
The primary aim of this research project is to examine changes in health outcomes following the introduction of a single or two cycling exercise sessions a week to kidney failure patients. We hypothesise that after 12 weeks of either once or twice weekly of cycling sessions per week, health outcomes are improved.
Interventions
A 3-month exercise intervention will be undertaken by all recruited participants. Group Aex will receive supervision of an exercise physiologist (EP) during the second dialysis session of each week. Participants are instructed to exercise at a rating of perceived exertion (RPE) of 13 on a Borg scale. Each exercise session will be 30-60 minutes long during the first two of dialysis treatment for that day. Progression of exercise duration over the 3 months period is expected, but will be determin
A 3-month exercise intervention will be undertaken by all recruited participants. Group Aex will receive supervision of an exercise physiologist (EP) during the second dialysis session of each week. Participants are instructed to exercise at a rating of perceived exertion (RPE) of 13 on a Borg scale. Each exercise session will be 30-60 minutes long during the first two of dialysis treatment for that day. Progression of exercise duration over the 3 months period is expected, but will be determined by participant response to the program. Using a stationary bike that is placed in front of the client’s dialysis chair, a warm up of 5-15 minutes will be completed followed by a 10 minute rest. After the rest clients will continue with exercise at the specified intensity for (up to) 30 to 60 minutes. In line with evidence based practice, participants will be constantly monitored by the exercise physiologist who will review the exercise prescription and aim to progressively update the loading (intensity) over time as individual participant adaptation occurs. Participants will be asked to refrain from adding extra exercise activities for the course of the intervention period.
Sponsors
Centre for Physical Activity in Ageing, Royal Adelaide Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
For the subjects to be included into the study, they need to satisfy the following criteria: * On maintenance haemodialysis for the past 3 months * Community residing; * Functionally independent; * Ambulatory with or without regular use of an assistive device; * Have no medical conditions or physical or cognitive limitations that would prohibit them from following instructions and participating safely in the tests; * Not identified as having recent falls * Medical clearance
Exclusion criteria
Contraindications * A recent significant change in the resting ECG suggesting infarction or other acute cardiac event * Recent complicated myocardial infarction (unless patient is stable and angina free) * Severe aortic stenosis * Suspected or known dissecting aneurism * Active myocarditis or pericarditis * Thrombophlebitis or intracardiac thrombi * Recent systemic or pulmonary embolus * Acute infections * Significant emotional distress (psychosis) * Resting diastolic blood pressure > 115 mm Hg or resting systolic blood pressure >200 mm Hg * Moderate valvular heart disease * Fixed rate pacemaker (rarely used) * Frequent or complex ventricular ectopy * Ventricular aneurism * Uncontrolled metabolic disease (e.g., diabetes, thyrotoxicosis or myxedema) * Neuromuscular, musculoskeletal, or rheumatoid disorders that are exacerbated by exercise * Pregnancy
Outcome results
None listed