Improving medicine adherence in kidney transplantation

In adults more than one month post-kidney transplantation, is a multi-factorial intervention including medicine review, DVD and health coaching more effective than usual care in improving immunosuppressant medicine adherence?

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000608662

Enrollment

Registered

2014-06-06

Start date

2014-09-22

Completion date

2015-10-13

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

More people require kidney transplants which are in short supply. It is imperative that people who have kidney transplants take their medicines as prescribed. Poor adherence to prescribed medicines can cause a 60% increased risk of kidney transplant failure. Rejection requires costly hospitalisations, laboratory tests and anti-rejection therapies with associated poor outcomes. This project will develop and test an intervention to help adults requiring a kidney transplant to take their medicines as prescribed. Better medicine adherence results in improved graft life, general well-being, and reduced health care expenditure. Our industry partners share this vision of improved health for people requiring kidney transplantation.

Interventions

All participants in the intervention group will receive a once only, one hour home visit comprising a home medicine review and a ten minute DVD to motivate people to take their medicines. Fortnightly ten minute telephone health coaching for three months will be conducted.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Educational / counselling / training

Masking

Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Comprehend English, and prescribed immunosuppressant medicines in kidney transplantation

Exclusion criteria

Adults living in supported accommodation (medicines are managed by staff)

Outcome results