None listed
Conditions
Brief summary
We hypothesize that cultural differences within the same race (Chinese) will lead to changes in opioid requirement after major abdominal surgery. This will be reflected by the differences in briefs and attitudes towards postoperative pain between patients living in the two cities.
Interventions
Sponsors
Eligibility
Inclusion criteria
Patients are eligible for the study if 1.18 and 80 years 2.undergoing major abdominal surgery requiring a wound incision > 10 cm in length. 3. All patients should have strong Chinese features and lived in their respective cities (Hong Kong or Hangzhou) for most of their lives.
Exclusion criteria
Patients are excluded if they: 1. do not agree to receive patient controlled analgesia (PCA) with morphine for at least three days after surgery 2. do not demonstrate adequate understanding on the principles involving the use of PCA during the preoperative visit. 3. Allergy to morphine, paracetamol or non-steroidal anti-inflammatory drugs. 4. Patients with pre-existing severe renal and liver disease, 5. chronic pain for > 3 months in the 6 months leading to surgery or who require opioid therapy in the preceding 2 weeks prior to surgery