Skip to content

Cultural Influence of Postoperative Pain

A prospective cohort comparing post-operative opioid requirement and other pain related behaviours and effects after major surgery in two Chinese populations from Hong Kong and Mainland China

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12614000601639
Enrollment
250
Registered
2014-06-05
Start date
2013-10-24
Completion date
2014-10-31
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We hypothesize that cultural differences within the same race (Chinese) will lead to changes in opioid requirement after major abdominal surgery. This will be reflected by the differences in briefs and attitudes towards postoperative pain between patients living in the two cities.

Interventions

Observational cohort study of pain perception and opioid requirements post major abdominal surgery in chinese adults that are culturally different. Observations will occur preoperatively and then twice daily for 3 days postoperatively.

Sponsors

Dr Alex Konstantatos
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

Patients are eligible for the study if 1.18 and 80 years 2.undergoing major abdominal surgery requiring a wound incision > 10 cm in length. 3. All patients should have strong Chinese features and lived in their respective cities (Hong Kong or Hangzhou) for most of their lives.

Exclusion criteria

Patients are excluded if they: 1. do not agree to receive patient controlled analgesia (PCA) with morphine for at least three days after surgery 2. do not demonstrate adequate understanding on the principles involving the use of PCA during the preoperative visit. 3. Allergy to morphine, paracetamol or non-steroidal anti-inflammatory drugs. 4. Patients with pre-existing severe renal and liver disease, 5. chronic pain for > 3 months in the 6 months leading to surgery or who require opioid therapy in the preceding 2 weeks prior to surgery

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 4, 2026