Effects of vitamin D on insulin resistance and endothelial dysfunction in diabetic patients with ischemic heart disease

Effects of vitamin D administration vs. placebo on insulin resistance, endothelial dysfunction and inflammatory markers in diabetic patients with ischemic heart disease

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000529640

Enrollment

100

Registered

2014-05-20

Start date

2014-04-20

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Hypovitaminosis D is a common problem and has negative effects on cardiovascular and metabolic disease like diabetes. So we want to try the effects of Vitamin D vs. placebo on inflammatory and cardiovascular markers and insulin resistance.

Interventions

Adminstration of a single dose parenteral vitamin D 300000 IU or placebo to diabetic patients with ischemic heart disease

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Eligibility

Sex/Gender

All

Age

25 Years to 62 Years

Healthy volunteers

Inclusion criteria

Patients with diagnosis of type 2 Diabetes mellitus on the basis of ADA criteria and ischemic heart disease based on angiography results

Exclusion criteria

1. History of hypersensivity to Vitamin D 2. Renal failure 3.Hypercalcemia 4. Pregnant women 5. Lactating women 6.Hepatic failure (Child-Pugh B and C)

Outcome results