Number of clots found in the arms of high risk surgical patients with a drip

Incidence of upper limb deep vein thrombosis in high risk surgical patients with cannulas

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12614000501640

Enrollment

Registered

2014-05-12

Start date

2014-06-02

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Aim: To investigate the relationship between dorsal hand/forearm cannulas and the development of an upper limb DVT in high risk surgical patients. Our sample size population will include 75 high risk patients (sample size of 62 + 10% for attrition) . Inclusion criteria are patients with an underlying malignancy, thrombophilias, previous surgery/trauma and over 65 years of age. As part of the inclusion criteria all patients will receive standard DVT prophylaxis surgery and have baseline bloods performed including a FBC,LFT, U+E and INR.Patients with a previous upper limb DVT, previous neck surgery/mastectomy/axillary clearance and thoracic outlet syndrome were excluded. Ultrasounds will be performed at enrolment (which is part of normal patient care) and at discharge to identify an upper limb DVT. Patients found to have an upper limb DVT will be placed on DVT protocol for treatment and will be followed up for 30 days for continuing management and monitoring of complications.

Interventions

We will enrol patients into the study. At enrolment the patient will have an ultrasound to see if they have a deep vein thrombosis (DVT). If they have a DVT they will be excluded from the study. They will have a second ultrasound at discharge to look for an upper limb DVT. If a patient is found to have an upper limb DVT, they will be treated with the standard DVT protocol.

Eligibility

Sex/Gender

All

Age

65 Years to 99 Years

Healthy volunteers

Inclusion criteria

- 65 years or older -a cannula in forearm/dorsum of the hand, inserted on admission -FBC and INR performed on admission -Patients with one or more of the following criteria: -underlying malignancy , -thrombophilias (Factor C deficiency, Factor S deficiency, Factor 5 Leiden mutation, Anti thrombin 3 deficiency, anti-phospholipid syndrome, Prothrombin 20210A mutation) -previous surgery or trauma A high risk surgical patient will be classified as a patient with two or more risk factors (one of the risk factors will be aged over 65).

Exclusion criteria

-previous or current trauma of upper limb or chest -previous or current upper limb, neck or axillary surgery -previous or current upper limb DVT -previous mastectomy -thoracic outlet syndrome -enlarged lymph nodes/tumours causing upper limb venous compression

Outcome results