Spinal Dexamethasone added to Bupivacaine and Caudal block in Pediatric Lower Extremity Orthopedic Surgery. A Prospective Comparative Study

The effect of spinal Dexamethasone added to bupivacaine versus caudal block on duration of block and postoperative analgesia in pediatric lower extremity orthopedic surgery

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000441617

Enrollment

Registered

2014-04-29

Start date

2012-11-26

Completion date

2013-10-24

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Addition of dexamethasone was found to prolong duration of spinal block in adults. The primary outcome of this study is comparing the duration of spinal block after addition of dexamethasone and the duration of caudal blockade, Secondary outcome is to assess quality of pain relief and muscle relaxation with hemodynamic stability and rapid recovery between the two groups.

Interventions

Group I (spinal group): dexamesthazone 0.1 mg/ kg added to hyperbaric bupivacaine (0.5 %) given interathecally Group II (caudal group): isobaric bupivacaine 1.2 ml/kg (0.25%) given caudally.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Healthy volunteers

Inclusion criteria

patients aged between 1 – 6 years, both males and females, ASA physical status I and II scheduled for lower extremity orthopedic surgical procedures were included in this study.

Exclusion criteria

refusal of the parents, infection at the site of the block, bleeding diathesis, children with neurological disorders, and children with known allergy to give local anesthetics.

Outcome results