Topical Glyceryl Trinitrate vs placebo in reducing perioperative pain and analgesic requirements in haemorrhoid banding

In those undergoing elective colonoscopy + banding of haemorrhoids, how does use of topical Glyceryl Trinitrate prior to banding versus placebo prior to banding, affect pain and analgesic requirements in the perioperative setting

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000349640

Enrollment

Registered

2014-04-01

Start date

2014-04-07

Completion date

2014-06-13

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This trial is aimed at determining if Glyceryl Trinitrate given by the surgeon prior to haemorrhoid banding during colonoscopy reduces peri-operative pain and need for analgesia when compared against placebo.

Interventions

Patients will have a standard dose of Gylceryl Trinitrate (standard dose = 1.5cm strip of the product where the active ingredient = 0.2% glyceryl trinitrate) applied to the perianal region immediately prior to haemorrhoid banding.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

15 Years to 100 Years

Healthy volunteers

Inclusion criteria

those undergoing elective colonoscopy + haemorrhoid banding

Exclusion criteria

allergies or contraindications to using glyceryl trinitrate

Outcome results