None listed
Conditions
Brief summary
To investigate and compare the presence, location and dimension of root resorption craters on human premolar teeth induced by jiggling movement with light and heavy forces for 12 weeks through Micro-CT scans. It is hypothesized that there is no statistically significant difference in the volume of the root resorption craters following twelve weeks application of jiggling and unidirectional forces on premolars in the same patient.
Interventions
The intervention under study involves Light (25g) and Heavy (225g) forces applied to a randomly allocated right or left upper first premolar with the direction of force alternating every 4 weeks over a 12 week period. Forces will be applied in one direction for 4weeks, the alternate direction for another 4 weeks and in the original direction for 4 weeks. These forces will be applied to the teeth via orthodontic brackets bonded to the maxillary first molars and first premolars, and 0.0017 x 0.02
The intervention under study involves Light (25g) and Heavy (225g) forces applied to a randomly allocated right or left upper first premolar with the direction of force alternating every 4 weeks over a 12 week period. Forces will be applied in one direction for 4weeks, the alternate direction for another 4 weeks and in the original direction for 4 weeks. These forces will be applied to the teeth via orthodontic brackets bonded to the maxillary first molars and first premolars, and 0.0017 x 0.025” Titanium Molybdenum Alloy (TMA) archwires in heavy force groups and 0.016” TMA wire springs in light force groups to produce 225 and 25 grams of tipping forces respectively on the upper first premolars throughout the 4 week period. Following enrolment, patients will be randomly allocated to one of four groups with the following parameters: Group LHJ: Light and Heavy Jiggling Movement Group (Transverse): A randomly allocated left/right first premolar will undergo light jiggling movements, while the contralateral premolar will undergo heavy jiggling movements in the transverse plane. Group PCLJ: Positive Control light (Unidirectional) and Light Jiggling Movement Group (Transverse): A randomly allocated left/right first premolar will undergo light unidirectional movements while the contralateral premolar will undergo light jiggling movements in the transverse plane. Group PCHJ: Positive Control Heavy (Unidirectional) and Heavy Jiggling Movement Group (Transverse): The randomly allocated left/right first premolar will have heavy unidirectional movements while the contralateral premolar will have heavy jiggling movements applied. Group HBIJ: Heavy Transverse and Vertical Jiggling Movement Group: The randomly allocated left/right first premolar will have heavy transverse jiggling movements while the contralateral premolar will have heavy vertical movements applied.
Sponsors
Prof. M. Ali Darendeliler
Study design
Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
12 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
1. Patient who requires removal of bilateral first premolar teeth as part of orthodontic treatment. 2. No previous reported or observed dental treatment to the teeth to be extracted 3. No previous reported or observed trauma to the teeth to be extracted 4. No previous reported orthodontic treatment involving the teeth to be extracted 5. No past and present signs and symptoms of any periodontal disease 6. No past and present signs and symptoms of bruxism 7. No significant medical history that would affect the dentition 8. No craniofacial and dentoalveolar syndromes 9. Completed root formation 10. Knowledge of subject’s residence since birth and history on fluoride consumption. 11. Sufficient room for the proposed root movements to be carried out
Exclusion criteria
1. Patient not requiring removal of bilateral first premolar teeth as part of orthodontic treatment. 2. History of dental/orthodontic treatment or trauma to the teeth to be extracted 3. Past and present signs and symptoms of any periodontal disease 4. Past and present signs and symptoms of bruxism 5. Any medical history that would affect the dentition 6. Any craniofacial and dentoalveolar syndromes 7. Inadequate root formation 8. Inadequate knowledge of subject’s residence since birth and history on fluoride consumption. 9. Insufficient room for the proposed root movements to be carried out
Outcome results
None listed