Skip to content

Halting Antipsychotic use in Long-Term care

Using person centred approaches to managing challenging behaviours in nursing home residents to reduce the use of antipsychotic medications and associated adverse events and improve quality of life.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614000309684
Acronym
HALT
Enrollment
140
Registered
2014-03-24
Start date
2014-04-30
Completion date
2015-09-15
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

There is strong evidence of adverse effects of polypharmacy in older people and of the benefits of deprescribing generally and antipsychotics particularly. Halting Antipsychotic use in Long Term Care (HALT) is a collaboration between consumers, residential aged care providers, staff, general practitioners, pharmacists, the Dementia Behaviour Management Advisory Service (DBMAS), Dementia Training Study Centre (DTSC), and specialists to reduce inappropriate antipsychotic medication use in long-term resident users and correspondingly to reduce complications, rates of decline and mortality without consequently increasing behavioural and psychological symptoms. We aim to demonstrate that HALT is a nationally applicable and sustainable model.

Interventions

1. Nursing home staff, GPs and pharmacists will undergo education and academic detailing on best practice in prescribing antipsycyhotic medications in older people and non-pharmacological approaches to managing challenging behaviours. GPs will undergo approximately 6 hours of academic detailing which will be accredited by the Royal Australian College of General Practitioners as a Clinical Audit attracting 40 CPD points. This will include a predisposing activity, approximately 3-4 hours total fac

1. Nursing home staff, GPs and pharmacists will undergo education and academic detailing on best practice in prescribing antipsycyhotic medications in older people and non-pharmacological approaches to managing challenging behaviours. GPs will undergo approximately 6 hours of academic detailing which will be accredited by the Royal Australian College of General Practitioners as a Clinical Audit attracting 40 CPD points. This will include a predisposing activity, approximately 3-4 hours total face to face time and evaluation activities at 6 months post detailing. In the instance that a GP does not require the CPD points and declines to undertake the RACGP activity, they will instead be offered a reimbursement of $25 for the time invested in attending to study tasks involving their patient. Pharmacists will undertake similar activities including a Group 2 continuing education module (8 points) accredited through the Pharmaceutical Society of Australia and the supply pharmacists will also be given the opportunity to undertake a Drug Use Evaluation activity (Group 3). 1 or 2 Registered Nurses at each participating nursing home will be given the role of "HALT Champion". These Champions will be the leaders of education and change within their workplaces. Their role will commence with a 3-day face to face workshop on person centred care, behavioural and psychological symptoms of dementia (BPSD) and how to manage these symptoms using non-pharmacological approaches. This workshop is interactive and provides practical strategies for implementation in the workplace. This education takes a "train the trainer" approach and following this workshop Champions will train the other care staff within their facility. They will do this using mini-tutorials at shift changeover (10 minutes), memo-cards, sharing of educational resources and at team meetings. The whole training process will take approximately 2 months and the aim of HALT is to have these new approaches to managing BPSD integrated into the culture of each nursing home resulting in sustained implementation of these strategies. Training of nursing home staff will be completed prior to the commencement of deprescribing. 2. Nursing home residents taking antipsychotic medications such as Risperidone, Haloperidol, Quetiapine and Olanzapine to manage Behavioural and Psychological Symptoms of Dementia will be identified and with agreement from their GP these medications will be deprescribed over a period of up to 3 months. Deprescribing protocols will be established for each resident participating in the trial by their GP and research pharmacist. Each dose reduction will take place at least 2 weeks apart until the drug is completely withdrawn.

Sponsors

UNSW Australia
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Educational / counselling / training
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Residential aged care facility: - Accredited high level care facility located across all areas of Greater Sydney region - At least 60 beds - Agreement for deprescribing procedure in their facility - Agreement to provide medication information for screening with identifiable information removed Participant: - At least 60 years of age - Residing in one of the participating residential aged care facilities - Antipsychotics scheduled regularly (taken more days per week than not) for at least 3 months - Informed written consent from participant or, where they cannot provide consent, from the participant's person responsible and the verbal assent of the participant - Agreement from treating GP to adhere to the deprescribing procedure - Availability of suitable interpreter if required

Exclusion criteria

Residential aged care facility: - Director of Nursing or management do not agree to participation - Facility is unable or unwilling to provide appropriate medication information for screening purposes (i.e., medication lists with identifiable information removed). Participant: - No consent and/or verbal assent - No agreement from GP responsible for prescribing antipsychotics - Inability to communicate with the participant, either due to English as a second language or other reasons, that would make planned assessments untenable. - Schizophrenia, bipolar disorder, psychotic depression or other current psychotic condition under active treatment - Total NPI score of at least 50 and; The Domain Total Score must be 12 in any two of these five domains: A. Delusions B. Hallucinations C. Agitation/Aggression E. Anxiety H. Disinhibition and; Occupational Disruptiveness must be a minimum of 4 in any two of the five domains mentioned above - Terminal illness, other medical condition that would make data collection impossible - resided at nursing home for < 1 month

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026