Ultrasound guided Transversus Abdominis Plane block: An evaluation of its efficacy in reducing post-op opioid requirements in Caesarean section

Parturients undergoing elective Caesarean section, Transversus Abdominis Plane block compared to intravenous Morphine via Patient Controlled Analgesia PCA to achieve better Postoperative pain control.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000262606

Enrollment

Registered

2014-03-11

Start date

2013-06-22

Completion date

2014-06-01

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The transversus abdominis plane (TAP) block is a new regional anaesthesia technique that provides analgesia to the peritoneum, skin as well as the muscles of the anterior abdominal wall. It is easy to perform with a high margin of safety, especially under ultrasound guidance. TAP blocks have been described as an effective component of multimodal postoperative analgesia for a wide variety of abdominal procedures including caesarean section. Current reports demonstrated its safety and efficacy in reducing opioids consumption. Post-op analgesia in patient undergoing emergency caesarean section has conventionally been a multi-modal analgesia comprising of morphine PCA, regular paracetamol and NSAIDs. These have resulted in large consumption of morphine which is excreted via breast milk. These also result in higher sedation score and higher incidence of post operative nausea and vomiting

Interventions

Arm 1 patients will receive TAP block, 0.25% Bupivacaine 20 ml bilaterally along with PCA Morphine Arm 2 patients will receive TAP block, 0.166% bupivacaine 30 ml bilaterally along with PCA Morphine TAP block is administered immediatly post caesarean section after skin suturing. PCA Morphine is made available in immediate post operative period in recovery room. PCA 1mg morphine per dose. lockout interval of 5 minutes. no background infusion and Maximum of 30 mg morphine per 4 hours.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Elective caesarean section. ASA 1 and ASA 2 patients. Patients receiving Spinal anaesthesia for surgery.

Exclusion criteria

Emergency caesarean sections. ASA 3 and ASA 4 patients. Morbidly Obese patients. Patients with local anaesthesia allergy

Outcome results