None listed
Conditions
Brief summary
There is an increasing body of evidence that the adoption of point of care (POC) guided coagulation and haemostatic management algorithms in the cardiac surgical patient population results in improved outcomes. We aim to critically evaluate our POC programme at the Gold Coast University Hospital (GCUH). In addition, we aim to evaluate the prognostic importance of baseline and perioperative humeral factors relating to haem catabolism (bilirubin/carboxy haemoglobin) in modulating haemostatic function and predicting post-operative outcomes in patients undergoing cardiac surgery
Interventions
ROTEM / Multiplate coagulation assessment and product transfusion protocol.
At 4 predefined time points a ROTEM/Multiplate panel of tests will be analysed:
1. Pre-operatively
2. 30 mins before coming off Cardiopulmonary Bypass
3. 10 mins after coming off CPB and after Protamine
4. On admission to ICU post-operatively
At each of these time points blood product replacement will be guided by the results. There is a predefined and validated algorithm.
In addition further tests will be done 10 min
ROTEM / Multiplate coagulation assessment and product transfusion protocol. At 4 predefined time points a ROTEM/Multiplate panel of tests will be analysed: 1. Pre-operatively 2. 30 mins before coming off Cardiopulmonary Bypass 3. 10 mins after coming off CPB and after Protamine 4. On admission to ICU post-operatively At each of these time points blood product replacement will be guided by the results. There is a predefined and validated algorithm. In addition further tests will be done 10 minutes after any haemostatic intervention. Further testing can be done at clinician discretion - i.e. In the presence of on-going bleeding further testing will be performed. Testing will cease once there is no further evidence of on-going bleeding .
Sponsors
Gold Coast University Hospital Critical Care Research Group
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
All patients undergoing cardiac surgery
Exclusion criteria
Age < 18 years
Outcome results
None listed