None listed
Conditions
Brief summary
To identify changes to the tear film and ocular surface in participants with meibomian gland dysfunction, in response to 3 treatments (on Days 1, 15 and 45) with intense pulsed light (E>Eye, France Medical Ltd Pty, Aust)
Interventions
At each visit, IPL is performed using a non-coherent, filtered broadband pulsed flash lamp (E>Eye, France Medical, Brisbane, Australia), at 9 - 13 J/cm^2 (according to skin type), in four pulses per eye (manufacturer's proprietary pulse profile), below the lower eyelid from the outer to inner canthus, while metal light-blocking goggles are worn to protect globe. Treatments are performed on Day 1, Day 15 and Day 45, with treatment duration of approximately 20 seconds.
Sponsors
The University of Auckland
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Dry eye symptoms (OSDI) and clinical evidence of Meibomian gland dysfunction by meibography
Exclusion criteria
Other anterior segment pathology Any conditions which preclude treatment by IPL
Outcome results
None listed