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Comparison of Surgical Results of 23-gauge Vitrectomy and Silicone Oil Tamponade Combined with and without Phacoemulsification

Safety and efficacy of 23-gauge vitrectomy and silicone oil tamponade combined with and without phacoemulsification in patients undergoing vitreoretinal surgery.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614000089639
Enrollment
38
Registered
2014-01-23
Start date
2009-01-09
Completion date
2011-12-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Purpose: To compare the clinical outcomes of 23-gauge vitrectomy and silicone oil tamponade combined with phacoemulsification and without phacoemulsification. Patients and Methods: This study included thirty eight eyes of 38 patients that underwent 23-gauge vitrectomy and silicone oil tamponade combined with and without phacoemulsification in SB Ankara Ulucanlar Eye Education and Research Hospital between January 2009 and December 2011. A complete ophthalmological examination including visual acuity, intraocular pressure with applanation tonometry, biomicroscobic examination findings, dilated pupil examination of the posterior segment, and ocular ultrasonography were evaluated at baseline and during follow-up period. Nineteen eyes of 19 cases that underwent 23-gauge vitrectomy and silicone oil tamponade combined with phacoemulsification were allocated to the group 1, and 19 eyes of 19 cases that underwent 23-gauge vitrectomy and silicone oil tamponade alone were allocated to the group 2. Results: There were 5 female (26.3%) and 14 male (73.7%) and the average age of patients was 48.8 years in group 1. There were 9 female (47.4%) and 10 male (52.6%) and the average age of patients was 49.4 years in group 2. Mean follow up period was 2.2 years (8-44 months). Visual acuities between two groups were statistically compared and significant changes were not found (P> 0.05). Recurrent retinal detachments were observed in 1 case (5%) in both groups. There was no statistically significant difference between two groups as a point of recurrent retinal detachments (P> 0.05). This study found higher rate of post-vitrectomy cataract progression (47.4%). Conclusion: Combined vitrectomy and phacoemulsification is safe and effective in vitreoretinal surgery and was associated with better visual acuity in postoperative period. There was no significant difference in the final visual acuity and in re-detachment rate.

Interventions

23-gauge vitrectomy and silicone oil tamponade combined with phacoemulsification were allocated to the group 1. Trans-scleral cannulas were placed through the pars plana in the superonasal, superotemporal, and inferotemporal quadrants, per standard vitrectomy protocol. In the combined group, phacoemulsification and IOL implantation was performed before PPV through a 2.75 mm superior clear corneal incision. Hydrophilic acrylic IOL inserted to the capsular bag in all cases. All eyes underwent cor

23-gauge vitrectomy and silicone oil tamponade combined with phacoemulsification were allocated to the group 1. Trans-scleral cannulas were placed through the pars plana in the superonasal, superotemporal, and inferotemporal quadrants, per standard vitrectomy protocol. In the combined group, phacoemulsification and IOL implantation was performed before PPV through a 2.75 mm superior clear corneal incision. Hydrophilic acrylic IOL inserted to the capsular bag in all cases. All eyes underwent core vitrectomy followed by removal of the posterior hyaloid membrane and vitreous traction. Retinal photocoagulation was performed in selected eyes. The fluid in the vitreous cavity was exchanged with silicone oil after vitrectomy. The approximate duration of procedure is 90 minutes.

Sponsors

SB Ankara Ulucanlar Eye Education and Research Hospital, Ankara, Turkey
Lead SponsorHospital

Study design

Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
38 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

The patients that underwent 23-gauge vitrectomy and silicone oil tamponade combined with and without phacoemulsification with following conditions included the study; rhegmatogenous retinal detachment, proliferative diabetic retinopathy with tractional retinal detachment, proliferative diabetic retinopathy with nonclearing vitreous hemorrhage, central retinal vein occlusion with vitreous hemorrhage and idiopathic epiretinal membrane.

Exclusion criteria

Patients with a history of prior vitreoretinal surgery and any corneal pathology were excluded from the study

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026