None listed
Conditions
Brief summary
To explore whether the relatively new form of resistance exercise which employs low resistances accompanied by restricting blood flood to targeted muscles (as know in Japan as Kaatsu training) can play a role in reducing the disability caused by inclusion body myositis.
Interventions
1 hour, 3 times/per 18 week strength exercise program in 2 phases targeting the quadriceps muscles in people in IBM. Sessions will held in as a group and supervised by a senior physiotherapist in a tertiary hospital.
Phase 1: establishing baseline. 5-6weeks of traditional moderate intensity strength training program (1 hour 3x/wk).
Exercises: squats, leg extensions, inner range quadriceps exercises, leg press.
repetitions: 8-12, 3 sets
Load: approx 60% of maximum lift
Phase 2: 12 weeks stren
1 hour, 3 times/per 18 week strength exercise program in 2 phases targeting the quadriceps muscles in people in IBM. Sessions will held in as a group and supervised by a senior physiotherapist in a tertiary hospital. Phase 1: establishing baseline. 5-6weeks of traditional moderate intensity strength training program (1 hour 3x/wk). Exercises: squats, leg extensions, inner range quadriceps exercises, leg press. repetitions: 8-12, 3 sets Load: approx 60% of maximum lift Phase 2: 12 weeks strength training at low intensity accompanied by partial occlusion of blood flow to quadriceps via blood pressure cuff placed around thigh. The cuff will remain inflated and around the thigh during exercises. exercises: as above repetitions: 15 load: 20-50% of maximum lift occlusion pressures: ~50% of systolic blood pressure
Sponsors
Sir Charles Gairdner Hospital Physiotherapy Department
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No
Inclusion criteria
Diagnosis of Inclusion Body Myositis A minimum of household ambulant with or without an aid Willing to participate exclusively in the studies exercise program (ie not participate in a formal concurrent thigh strengthening program) Full range of knee extension
Exclusion criteria
Non-ambulant, unable to walk 10 meters Peripheral vascular disease and/or compromised lower limb circulation Coexistent neurological or psychiatric disease Severe patella-femoral pain, knee osteoarthritis Unstable medical condition - unstable angina, uncontrolled diabetes, uncontrolled hypertension
Outcome results
None listed