Research on nasopharyngeal carcinoma with contrast-enhanced ultrasonography

Diagnostic accuracy of contrast-enhanced ultrasonography versus MRI for primary nasopharyngeal carcinoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12614000067673

Enrollment

Registered

2014-01-21

Start date

2013-01-01

Completion date

2015-03-29

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this prospective study was to determine whether ultrasonography represents a potential screening method for suspected cases of nasopharyngeal carcinoma, and to evaluate the imaging information provided by ultrasonography that can be applied to the clinical staging and treatment of nasopharyngeal carcinoma.

Interventions

Patients suspected of having nasopharyngeal carcinoma (NPC) will do ultrasonography (US) and magnetic resonance (MR) imaging. A diagnosis was obtained from an endoscopic biopsy that was collected from the suspected tumor or a normal nasopharynx. US examinations and MR imaging were performed prior to the nasopharyngeal endoscopy so that the biopsy would not affect the images of the nasopharynx. There was approximately 30 minutes assessed on a single occasion only.

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Suspicion of NPC was based on the presence of metastatic cervical lymph nodes and/or a nasopharyngeal abnormality accompanied by nonspecific symptoms (e.g., epistaxis, nasal obstruction, hearing loss).

Exclusion criteria

Patients were excluded if they did not successfully undergo US, MR imaging, and an endoscopic biopsy, or if a non-NPC tumor of the nasopharynx was diagnosed.

Outcome results