None listed
Conditions
Brief summary
Coronary artery disease patients with normal lipids and below-normal HDL will be recruited in one of the three arms. They will be given either Pakistani or american almonds or no intervention if they are randomized in the control group. Blood will be drawn at baseline, six and twelve weeks for lipid profiling. HDL-raising efficacy of almonds and comparison of the two almond varieties will be analyzed
Interventions
Arm 1: No intervention
Arm 2: Pakistani almonds (10 gm per day for 12 weeks)
Arm 3: American almonds (10 gm per day for 12 weeks)
The content of different almond varieties vary which might or might not lead to difference in biological activity.
Total duration of intervention is 12 weeks.
Regular phone calls (twice a week) were made to monitor compliance.
Sponsors
Aga Khan University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No
Inclusion criteria
Coronary artery disease with LDL < = 100 mg/dl and HDL < = 40 mg/dl (male) or < = 50 mg/dl (female)
Exclusion criteria
All patients recently presented with Acute Myocardial infarction (within last 5 weeks). Patients with nut allergy Patients already taking regular nuts Regular Smokers
Outcome results
None listed