None listed
Conditions
Brief summary
This is a pilot randomised control trial (RCT) to investigate whether using nasal Iota Carrageenan spray is protective against the development of colds caused by rhinovirus. The regular spraying of Iota Carrageenan may reduce the incidence of rhinovirus infections by blocking the binding of virus particles to nasal cells. If successful, the pilot study data will be used as the basis of a larger study to examine whether Iota Carrageenan can reduce rhinovirus infections among asthmatic adults.
Interventions
A nasal spray containing saline solution and 1.6 mg/ml carrageenan will be taken by participants in the active group during cold season. Each participant will take one spray into each nostril 3 times each day for 8 weeks. The participants will take a daily record of cold symptoms and a nasal swab will be taken at the beginning and end of the study, as well as when cold symptoms develop, to ascertain levels of rhinovirus in the nose.
Sponsors
Julian Crane
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
At least one cold infection reported in the previous year
Exclusion criteria
Not using any other nasal sprays during the study period Previous sensitivity to carrageenan spray.
Outcome results
None listed