None listed
Conditions
Brief summary
A recent pilot study using a Kanuka honey product for Acne showed that over 80% of participants self reported improvement, therefore this study treatment has the potential to be an effective treatment for Acne symptoms. In this study 138 adults with Acne will either wash their face with Protex Soap Fresh Antibacterial alone twice daily, or apply topical Kanuka honey to areas of Acne on their face for 30-60 minutes twice a day prior to washing with Protex Soap Fresh Antibacterial for 12 weeks. At baseline and after 4 weeks and 12 weeks the patient's Acne will be assessed to look at changes in severity. Participants will complete a diary for 12 weeks to record their daily treatment applications and weekly severity assessment. Subjects will complete a Dermatology Quality of Life questionnaire at all visits, to note any changes in quality of life. A visual analogue scale will be completed to note any improvement or worsening of a patient's Acne at Visits 2 and 3. This study will investigate the effectiveness of Kanuka honey in treating Acne, potentially improving the health outcomes of those with the condition, and will contribute to the knowledge base around the use of honey for the treatment of skin conditions.
Interventions
Topical medical grade Kanuka honey with 10% glycerin content applied to the affected facial area twice daily for 30-60 minutes per application, for twelve weeks. Patients will then wash area with Protex Soap Fresh Antibacterial medicated soap as per manufacturer's instructions, twice daily after honey treatment. A patient diary will record applications during the treatment period.
Sponsors
Honeylab Ltd
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
16 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
Aged 16-40 years at the time of enrolment Baseline facial IGA (investigator Global Assessment) of 2 or greater
Exclusion criteria
Any significant systemic illness Current requirement for systemic corticosteroid or has had systemic corticosteroid in the 4 weeks prior to Visit 1 Current requirement for oral antibiotic treatment for acne, or has had oral antibiotic treatment for acne in the 4 weeks prior to Visit 1 Current requirement for topical corticosteroid or topical antibiotics for the treatment of acne Change in oral contraceptive therapy in the last 3 months A systemic retinoid in the 2 months prior to Visit 1 Known or suspected allergy to honey, or Protex Soap Fresh Antibacterial Any other condition which, at the investigators discretion, it is believed may present a safety risk or impact the feasibility of the study or the study results
Outcome results
None listed