An observational study comparing protocol estimated values to the measured values of mean arterial basal blood pressure

An observational study to assess the agreement between protocol estimated values and directly measured values for the basal blood pressure in a cohort of patients who recently underwent direct measurements of their resting arterial blood pressure.

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613001382763

Enrollment

150

Registered

2013-12-17

Start date

2013-12-18

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Few patients admitted to the intensive care unit (ICU) have a previous record of directly measured BP during nighttime or resting (hereto referred as basal) state. Therefore, the usual hemodynamic targets in ICU are broadly based on values relevant to the general population. Individualising these targets could vastly improve management of critically ill patients. A validated protocol to estimate a patient’s baseline BP would enable this tailored therapy for the patients. The main purpose of this study is to assess the agreement (or the difference) between a protocol-estimated value and a directly measured value for the resting BP in a cohort of patients who recently underwent direct measurements of their resting arterial BP. In this study, we hypothesise that the directly measured and protocol-estimated BP values will correlate well with minimal bias.

Interventions

This is a retrospective observational cohort study among patients who attended our hospital cardiology department. We will enrol only those patients who recently underwent nighttime ambulatory blood pressure (BP) monitoring (within the last 2 years). These BP measurements will be considered as direct measurements of basal arterial BP. For all enrolled patients, a blinded study investigator who is not aware of the direct measurements, will then estimate the basal mean arterial BP according to a

Eligibility

Sex/Gender

All

Age

40 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients with recent outpatient ambulatory BP monitoring within last 2 years AND 2 to 5 recorded BP measurements in a routine/follow up clinic BP within last three years

Exclusion criteria

Patients with end stage renal disease and/or receiving dialysis

Outcome results