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Evaluation of intraocular pressure changes during anesthesia

"Intraocular pressure changes during sevoflurane and desflurane anesthesia in patients requiring non-ophthalmic surgery: randomised, controlled trial"

Status
Terminated
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12613001359729
Enrollment
100
Registered
2013-12-12
Start date
2009-09-07
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

American Society of Anesthesiologists Classification (ASA) 1-2 patients scheduled for non-ophtalmic surgery under general anesthesia included to the study. Patients are allocated in one of the groups either sevoflurane or desflurane. Intraocular pressure changes measured with perkin's tonometer before surgery, after induction, after intubation at every 15 min during the surgery, after extubation.

Interventions

Desflurane is the intervention of the study. It is very frequently used inhalant anesthetic. It will be inhaled approxiamately 1 hour for the duration of the surgical procedure at 1 Minimum alveolar concentration (MAC) .

Sponsors

Meram Medical School
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Diagnosis

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Without any eye disorder, not using eye medications, ASA 1-2, scheduled for non-ophtalmic surgery general anesthesia. Mallampathy score less than 3.

Exclusion criteria

DM, HT, Cardiovascular problems,known eye disorders or using some eye medicatons,refusal of the study, immunulugic disease, rheumatologic disease history, laparoscopic procedures, hard to ventilate and intubate, succinylcholine use during induction of anesthesia

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026