Incidence of postoperative residual curarization in the post-anaesthesia recovery unit

A study on the incidence and prevalence of postoperative residual curarization (PORC) in the post anaesthetic care unit (PACU) in female patients who underwent a general anaesthetic and received neuromuscular blocking drug (NMBD) for major gynaecological, breast , reconstructive or aesthetic surgery.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613001357741

Acronym

Incidence of PORC in PACU

Enrollment

250

Registered

2013-12-11

Start date

2013-12-03

Completion date

2014-11-20

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We aimed to characterize and define the incidence and prevalence of postoperative residual curarization (PORC) in the post anaesthetic care unit (PACU) of our tertiary referral women’s centre in 250 patients after major gynaecological, breast and aesthetic surgery. Our primary outcome variable is the incidence of PORC in awake extubated patients 10 min post-PACU arrival, where a TOF ratio <0.9 is used as criteria for defining postoperative residual weakness. Secondary outcome measures studied are the presence of side effects (nausea and vomiting), adverse respiratory events, time to PACU discharge readiness and actual length of PACU stay.

Interventions

The incidence of PORC in awake extubated patients 10 min post-PACU arrival. (defined as a nerve stimulation Train Of Four ratio <0.9 for postoperative residual weakness.)

Eligibility

Sex/Gender

All

Age

21 Years to 80 Years

Healthy volunteers

Inclusion criteria

ASA I-III patients who underwent a general anaesthetic for major gynaecological, breast , reconstructive or aesthetic surgery, in whom a neuromuscular blocking drug was administered.

Exclusion criteria

< 21 years, had underlying neuromuscular disease, use of medication known to interfere with neuromuscular transmission.

Outcome results