None listed
Conditions
Brief summary
It has been shown that early placement of an intravenous cannulation in children anesthetized with sevoflurane movement was greater, and the incidence of laryngospasm was higher. The aim of this study is determine the optimal time for safe intravenous cannulation in children induced with sevoflurane and nitrous oxide after midazolam premedication. Children aged 2-6 years, ASA physical status I, will scheduled for an elective procedure under general anesthesia will recruited. Patients will received oral midazolam(0.5 mg) Inhalational anesthesia will induced with sevoflurane nitrous oxide via mask, then intravenous cannulation will attempted. The time for intravenous cannulation will determined by the use of up-and-down method using 15 s as a step size. Intravenous cannulation without any movement, or laryngospasm will considered successful. The up-and-down sequences will analyzed by the probit test. The sample size calculation will based on Dixon's method that needs at least six pairs of failure-success
Interventions
Children will premedicated with oral midazolam (0.5 mg/kg) mixed in a small amount of strawberry syrup (total volume of 5 ml).
General anesthesia was induced with sevoflurane and nitrous oxide via face mask .For the first child, four minutes after the loss of eyelash reflex, the intravenous cannulation was attempted by an experienced anesthetist. At the time of intravenous canulation attempt, an independent observer who was blinded about predetermined canulation time, rated the movement ac
Children will premedicated with oral midazolam (0.5 mg/kg) mixed in a small amount of strawberry syrup (total volume of 5 ml). General anesthesia was induced with sevoflurane and nitrous oxide via face mask .For the first child, four minutes after the loss of eyelash reflex, the intravenous cannulation was attempted by an experienced anesthetist. At the time of intravenous canulation attempt, an independent observer who was blinded about predetermined canulation time, rated the movement according to a scale (0= no movement 1= slight extremity tensing, 2= extremity withdrawal, 3=generalized movement). Intravenous cannulation without any laryngospasm or movement was considered successful.The intravenous cannulation time of the next patient was determined by the use of up-and-down method (15 s as a step size).The observation was concluded after intravenous cannulation and the case proceeded as per routine. The sample size of the patients is based on Dixon’s up-and-down method that requires at least six pairs of failure success.
Sponsors
Necmettin Erbakan University
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Healthy volunteers
Yes
Inclusion criteria
Participant are children with ASA physical status I and scheduled for an elective procedure under general anesthesia without prior intravenous cannulation were selected.
Exclusion criteria
history of an upper respiratory tract infection,abnormal airway, reactive airway disease,
Outcome results
None listed