Skip to content

The effect of a bout of resistance exercise on pressure pain sensitivity in knee osteoarthritis

Does a bout of resistance exercise evoke an analgesic response in individuals with knee osteoarthritis and young and old healthy individuals

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12613001224718
Enrollment
45
Registered
2013-11-06
Start date
2011-09-08
Completion date
2013-11-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study investigates the analgesic effects of a bout resistance exercise on pressure pain thresholds and pressure pain tolerance in healthy participants and participants with knee osteoarthritis. The pain measures will be assessed at baseline and will be repeated following a bout of resistance exercise. Questionnaires concerning physical activity, pain, disability and injury will be completed by the participants.

Interventions

Single bout of resistance exercise (i.e. strength training) comprising 3 exercise, 3 sets of 10 repetitions at 60% of maximum (i.e. 60% of 1 repetition maximum), 1 minute rest between sets. This intervention was delivered under 2 conditions, either 3 lower body exercises (leg press, leg curl, calf raise) or 3 upper body exercises (chest press, supported row, lat pulldown). Upper and lower body exercise bouts were completed separately with 1 week washout in between bouts.

Sponsors

Benjamin Barry
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Any individual diagnosed with knee osteoarthritis by a general practitioner or rheumatologist (i.e. osteoarthritis group). For the healthy control groups, young (18-35) and older (50 and older) people who are unaffected by osteoarthritis.

Exclusion criteria

A history of chronic pain or musculoskeletal or neuromuscular disorders with the exception of osteoarthritis of one or both knees only (osteoarthritis of other joints will mean exclusion). Any absolute or uncontrolled cardiovascular contraindications

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026