The comparison of the efficiency of Saddle Block and Caudal Anesthesia in postoperative analgesic consumption and patient comfort using levobupivacaine in patients undergoing transurethral prostate resection (TURP).

Saddle Block is more Advantageous than Caudal Block in Patients Undergoing Transurethral Prostate Resection

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613001115729

Enrollment

Registered

2013-10-04

Start date

2011-03-03

Completion date

2011-10-27

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Objective: Caudal Anesthesia and Saddle Block are preferential methods in transurethral prostate resection (TURP). We aimed to compare the efficiency of Saddle Block and Caudal Anesthesia in postoperative analgesic consumption and patient comfort using levobupivacaine. Methods: Fifty ASA I-III patients were divided into two groups. Using 0.5% 10 mg levobupivacaine and 25 micrograms fentanyl, Saddle Block was performed by L4-5 interspace for Group S and using 14 ml 0.5% levobupivacaine and 25 micrograms fentanyl, Caudal Anesthesia was applied for Group C. Sensorial and motor block initial time, satisfaction of the patients, painless interval after operation and the total postoperative analgesic requirements for 24 hours were recorded. Results: The age, gender, body mass index, operation time and postoperative painless interval time were similar between the groups (p>0.05). The initial time of sensory block in Group S was statistically lower than in Group C (p=0.001). The comfort score in Group S was higher than in Group C (p=0.0001). The total amount of postoperative analgesic requirement for 24 hours in group S was found to be lower than in Group S (p=0.001). Motor block was developed in Group S and no motor block in Group C (p=0.0001). Hemodynamic parameters were similar in both groups (p>0.05). Conclusions: Using levobupivacaine and fentanyl, Saddle Block was found more advantageous than Caudal Block regarding patient comfort score, postoperative total analgesic requirement for 24 hours and initial time of sensorial block in patients undergoing TURP.

Interventions

Fifty adult male patients who were planned to undergo a transurethral prostate resection (TURP) under regional anesthesia due to benign prostate hypertrophy were included in the study with informed consent obtained from each patient. This is a prospective, randomized, and double-blind study including cases with Caudal Block (group C) or Saddle Block (GroupS) for TURP. Group S 5% 10 mg levobupivacaine and 25micrograms fentanyl were administered to the subarachnoid space by L4-5 interspace once

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

Male

Age

45 Years to 60 Years

Healthy volunteers

Inclusion criteria

50 adult male patients who were planned to undergo a transurethral prostate resection (TURP) under regional anesthesia

Exclusion criteria

Patients who rejected regional anesthesia, who had a neurological deficit, local or systemic infection, a past medical history of allergy to local anesthetics, coagulopathy, a high intracranial pressure, severe cardiac disease, who were on NSAID, acetylsalicylic acid, oral anticoagulants, heparin, LMWH, and inhibitors of thrombocyte aggregation, or who were hypovolemic and had an inadequate block after the application were excluded from the study.

Outcome results