Assessment of fat free mass in older adults: a comparison of body composition methods in an Asian and European population

Validation of Bioelectrical Impedance Spectroscopy [BIS] for assessment of fat free mass in a Chinese Asian and European Caucasian adult population: comparison with dual energy x-ray absorptiometry (DeXA)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613001111763

Acronym

VALBIO_Asia

Enrollment

407

Registered

2013-10-03

Start date

2013-10-07

Completion date

2014-06-06

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Background: The assessment of body composition is important to identify individuals at risk of muscle loss. Commercial bioelectrical impedence monitors are widely available, but provide only an indirect measure of fat free mass based on algorithms derived in Caucasian populations. Objective: The objective of this study is to derive population specific predictive algorithms for the calculation of fat free mass and fat mass using a simple assessment device. Design: This is a cross-sectional study, 400 participants, aged 45-70 years, of Asian Chinese (n=200) or Caucasian European (n=200) ethnicity will be recruited. Fat free mass (FFM) and fat mass (FM) will be measured on a single occasion using 3 BIA/BIS devices, DeXA and pQCT. Findings: The findings from the study will enable rapid assessment of fat free mass in different target populations.

Interventions

Participants will undertake tests and measurements with 3 BIA/BIS devices (DF50, SFB7, SFB7mini prototype), DeXA, and pQCT. All the measurements will be taken on one occassion The approximated time is 1 hour to 1hr 15min

Eligibility

Sex/Gender

All

Age

45 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

- Asian (Ethnic Chinese, mainland China, Hong Kong, Taiwanese), and - Caucasian (Ethnic European) - adult men and women; n=100 men, n=100 women; in both groups - Aged 45-70 years - 18-40kg/m2 - healthy, by self-report

Exclusion criteria

- significant current disease, including muscle wasting syndromes - morbid obesity (BMI>40kg/m2) - presence of a cardiac pacemaker - pregnancy

Outcome results