Serum levels range of myocardial enzymes following urologic procedures.

The impact of urologic surgical procedures on the serum levels of myocardial enzymes: CPK, CK-MB, SGOT and LDH.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613001071718

Acronym

MESLeCUS (Myocardial Enzymes Serum Levels Changes in Urological Surgery)

Enrollment

300

Registered

2013-09-25

Start date

2014-01-13

Completion date

2015-09-30

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Elevation of serum levels of myocardial enzymes is considered to be a specific finding for acute myocardial infarction (AMI). However, many other conditions have been proposed to affect the level of these enzymes. This study was designed to determine the changes in the levels of LDH, SGOT, CPK and CK-MB in patients who undergo urological surgery with no medical history of myocardial disease.

Interventions

Measurement of the range of CPK, CK-MB, LDH and SGOT serum levels following urologic surgical procedures. The serum levels of these enzymes are going to be measured 24 hours pre- and 24 and 72 hours post-operatively.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Patients with no medical history of myocardial disease who undergo urologic surgical procedures, including open, endoscopic and laparoscopic surgery. 2. Age over 18 years old.

Exclusion criteria

1. History of coronary disease. 2. Evidence of acute myocardial infarction (AMI), diagnosed by clinical, laboratory (normal troponin levels) and electrocardiographical findings.

Outcome results