Modulation of experimental pain using non-invasive brain stimulation.

The effect of transcranial direct current stimulation on sensitivity to experimental pain in healthy adults.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000995774

Enrollment

Registered

2013-09-06

Start date

2013-09-09

Completion date

2014-06-02

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Recent development of non-invasive brain stimulation techniques has provided further insight into human nervous system function. Transcranial direct current stimulation (tDCS) is one such technique, which involves delivering mild electrical current to the brain via surface electrodes. Further research, however, is required to evaluate the effects of consecutive daily application of tDCS on human sensory function. Consequently, the aim of this research project is to investigate whether five consecutive daily sessions (1 session / treatment day) of tDCS can improve sensory function in a healthy human population. The results of this study will lead to a better understanding of human sensory function modulation.

Interventions

Transcranial direct current stimulation Dose: 2mA Duration: 30min Mode of administration: 5 consecutive daily sessions (1 session/ treatment day) applied over the dominant motor cortex using a direct current stimulator (Chattanooga Ionto, Tennessee, USA).

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy Both males and females Aged 18-65

Exclusion criteria

Persistent neurological condition, current abuse of elicit substances and alcohol, pregnancy, does not understand English, magnetic/ metallic pieces inside skull, implanted metal devices (pacemaker, cochlear device, medication pumps, nervous system stimulators), cardiac disease, skin lesion near electrode sites, have ever experienced a convulsion or seizure.

Outcome results