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Effects of 8 weeks of aerobic or modified football training on skeletal muscle markers of mitochondrial functioning, systemic inflammation and glucose regulation

Effects of 8 weeks of aerobic or modified football training on mitochondrial biogenesis, systemic inflammation and glucose regulation within sedentary, middle-aged men.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12613000874718
Enrollment
30
Registered
2013-08-06
Start date
2011-09-30
Completion date
2011-10-07
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to determine the chronic effects of a generic gym based exercise mode (cycle) in comparison to modified touch football on markers and signalling processes associated with the development of type II diabetes (T2DM) and cardiovascular disease (CVD). Additionally, the current study will assess changes involving, body composition, skeletal muscle glucose uptake, anti- and pro-inflammatory processes, and risk markers associated with T2DM and CVD.

Interventions

Physical Activity and Nutritional Documentation All participants will be provided with an exercise diary for the documentation of physical activity external to the study. Additionally, an exercise log will be kept by the Chief Investigator, which will consist of exercise information pertaining to the actual work completed during training sessions. Participants will also be informed of the importance of maintaining normal diet and nutritional patterns including macro- and micro-nutrient consumpti

Physical Activity and Nutritional Documentation All participants will be provided with an exercise diary for the documentation of physical activity external to the study. Additionally, an exercise log will be kept by the Chief Investigator, which will consist of exercise information pertaining to the actual work completed during training sessions. Participants will also be informed of the importance of maintaining normal diet and nutritional patterns including macro- and micro-nutrient consumption (contribution from CHO, fat, protein; vitamin/mineral supplementation), time of consumption (lateness of evening meal), quantity of serving (dietary caloric restriction), type of preparation (cooking oils used, boil/steam/raw, etc), and alcohol consumption (type and quantity). The cycling and modified football training programs will consist of 4 mesocycles (blocks) of 2 weeks, with session duration and intensity steadily progressing from one mesocycle to the next. This protocol will allow for appropriate training adaptations to occur prior to an increase in intensity, thus allowing all participants to complete all exercise sessions in a comfortable manner. Aerobic (cycling) Training Program The aerobic exercise program will involve participants performing continuous a cycling exercise on a stationary ergometer for a total of 3 sessions per week. Each session will be monitored by an exercise physiologist. During the 8 weeks, exercise duration will increase from 30 to 45 min, and intensity will be increase from 70 to 80% of maximal heart rate. In each training session pedalling resistance, rpm and heart rate will be recorded at 5 minute intervals and at the conclusion an overall RPE will be obtained. Modified Football Training Program The modified football program will involve participants exercising for 3 sessions per week of touch football games. Each session will be monitored by an exercise physiologist. Additionally, during one training session per week GPS units will be utilised to identify any improvements in velocity and total distance covered throughout the exercise program. During the 8 weeks, total session duration will increase from 30 to 45 min, and total game play (intensity) will increase from 22 to 38 minutes. In each training session heart rate will be recorded during the rest intervals and at the conclusion an overall RPE will be obtained.

Sponsors

Charles Sturt University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Prevention

Eligibility

Sex/Gender
Male
Age
35 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

Subject Population The study population will comprise of 36 sedentary, Caucasian male subjects aged 35-60 y, who are in a non-diseased state. All testing procedures and training programs will be conducted at the CSU laboratory and subjects will be recruited from regional Bathurst areas. All subjects will be randomized into exercise protocols including an aerobic, modified football, or control protocol, allowing 12-15 subjects in each protocol to complete the allocated training intervention.

Exclusion criteria

Subject recruitment will ensure a non-smoking sample population group representative of a sedentary lifestyle, but not clinically diagnosed with any pre-existing CVD or metabolic disorders. Participants with orthopaedic limitations will also be advised against study involvement due to the musculoskeletal demands of the respective exercise protocols.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 4, 2026