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Does the use of a larger femoral head in total hip replacement increase the amount of wear of the plastic liner or the amount of movement of the acetabular cup?

Radiostereometric analysis of polyethylene wear and acetabular component migration following randomisation to either a large 36 mm or standard 28 mm diameter metal on highly cross-linked polyethylene articulation in primary total hip replacement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12613000860763
Enrollment
56
Registered
2013-08-05
Start date
2002-12-10
Completion date
2011-07-22
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This randomised controlled trial aims to determine whether a primary total hip replacement prosthesis with a larger 36 mm diameter metal on highly cross-linked polyethylene articulation is associated with significantly greater polyethylene wear and acetabular component migration. This study utilises radiostereometric analysis, the most sensitive radiographic technique available to measure wear and migration in vivo.

Interventions

Primary total hip replacement using a 36 mm metal on highly cross-linked polyethylene articulation. This is a surgical procedure where the femoral head is removed and replaced by a metal prosthetic femoral head (which in this situation has a diameter of 36 mm), which is attached to a femoral stem inserted into the femur. The head then articulates with a plastic (highly cross-linked polyethylene) liner in a metal acetabular shell, which is inserted into the acetabulum. The duration of the operati

Primary total hip replacement using a 36 mm metal on highly cross-linked polyethylene articulation. This is a surgical procedure where the femoral head is removed and replaced by a metal prosthetic femoral head (which in this situation has a diameter of 36 mm), which is attached to a femoral stem inserted into the femur. The head then articulates with a plastic (highly cross-linked polyethylene) liner in a metal acetabular shell, which is inserted into the acetabulum. The duration of the operation is between about 45 minutes and 4 hours, depending on the complexity of the operation. During the operation tiny tantalum beads are inserted into the polyethylene liner and periprosthetic bone to enable determination of polyethylene wear and acetabular component migration using a highly sophisticated radiographic technique, namely radiostereometric analysis.

Sponsors

Prof Donald Howie
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
65 Years to 74 Years
Healthy volunteers
No

Inclusion criteria

1. undergoing primary total hip replacement through posterior approach 2. diagnosis of osteoarthritis 3. walking ability restricted only by hip pathology

Exclusion criteria

1. previous infection 2. abnormal acetabulum 3. abnormal abductor mechanism 4. expected leg length inequality >5 cm 5. neuromuscular disease affecting hip

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026