None listed
Conditions
Brief summary
This randomised controlled trial aims to determine whether a primary total hip replacement prosthesis with a larger 36 mm diameter metal on highly cross-linked polyethylene articulation is associated with significantly greater polyethylene wear and acetabular component migration. This study utilises radiostereometric analysis, the most sensitive radiographic technique available to measure wear and migration in vivo.
Interventions
Primary total hip replacement using a 36 mm metal on highly cross-linked polyethylene articulation. This is a surgical procedure where the femoral head is removed and replaced by a metal prosthetic femoral head (which in this situation has a diameter of 36 mm), which is attached to a femoral stem inserted into the femur. The head then articulates with a plastic (highly cross-linked polyethylene) liner in a metal acetabular shell, which is inserted into the acetabulum. The duration of the operation is between about 45 minutes and 4 hours, depending on the complexity of the operation. During the operation tiny tantalum beads are inserted into the polyethylene liner and periprosthetic bone to enable determination of polyethylene wear and acetabular component migration using a highly sophisticated radiographic technique, namely radiostereometric analysis.
Sponsors
Study design
Eligibility
Inclusion criteria
1. undergoing primary total hip replacement through posterior approach 2. diagnosis of osteoarthritis 3. walking ability restricted only by hip pathology
Exclusion criteria
1. previous infection 2. abnormal acetabulum 3. abnormal abductor mechanism 4. expected leg length inequality >5 cm 5. neuromuscular disease affecting hip