None listed
Conditions
Brief summary
the study will test the value of adding aerosolized albuterol to lung recruitment during mechanical ventilation of patients with ALI to improve alveolar fluid clearance and oxygenation
Interventions
we will test the value of adding aerosolized albuterol sulphate 5mg dissolved in 10 ml sterile saline and nebulised by connecting the nebulizer to the endotracheal tube during mechanical ventilation of patients with acute lung injury (ALI) together with lung recruitment maneuver which is done in the form of increasing the positive end expiratory pressure (PEEP) 10 cm H2O above the lower infliction point for 15 minutes or 10 cmH2O above the pre-recruitment PEEP to be repeated every four hours f
we will test the value of adding aerosolized albuterol sulphate 5mg dissolved in 10 ml sterile saline and nebulised by connecting the nebulizer to the endotracheal tube during mechanical ventilation of patients with acute lung injury (ALI) together with lung recruitment maneuver which is done in the form of increasing the positive end expiratory pressure (PEEP) 10 cm H2O above the lower infliction point for 15 minutes or 10 cmH2O above the pre-recruitment PEEP to be repeated every four hours for five to seven successive days in a trial to improve alveolar fluid clearance and improve oxygenation in these patients
Sponsors
south valley university
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
patients with acute lung injury due to surgical and non surgical causes
Exclusion criteria
hemodynamic instability , patients on b-blockers therapy
Outcome results
None listed