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The causes of pneumonia in paediatric patients in North Queensland – should we reconsider our antibiotic strategy?

Retrospective cohort study of children with pneumonia admitted to our tertiary referral centre from the North Queensland region, assessing the incidence and treatment of multi-resistant organisms, and whether the statewide antibiotic guideline is suitable for our patients.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12613000824763
Enrollment
250
Registered
2013-07-26
Start date
2014-03-24
Completion date
2014-05-28
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will be conducted as a retrospective audit at the Townsville Hospital and will utilise existing hospital records and databases to answer a number of important clinical questions including: 1. What are the identified aetiologies for pneumonia in children in Townsville? 2. In what proportion of cases does the treatment of pneumonia conform to the published guidelines? Where it is not, is a reason for this identified? 3. Are the empirical antibiotics used in the Townsville Hospital for treatment of pneumonia in children appropriate? In what percentage of cases are organisms not sensitive to initial treatment identified (or change of antibiotics required when the patient does not respond)? 4. Are there clinical, demographic, geographic or other features which would indicate that empirical antibiotic treatments recommended in the guidelines are inappropriate in our setting?

Interventions

Assessing the groups in which empirical broader spectrum therapy than that recommended by the statewide guideline may be appropriate, by describing the incidence of drug-resistant disease in our community. Data was collected on all episodes of pediatric pneumonia admitted to the Townsville Hospital between Jan 2009-Jun 2013. This cohort received a variety of antibiotics due to the previous lack of any protocol, and some were commenced by local specialists on broader treatment earlier in the cour

Assessing the groups in which empirical broader spectrum therapy than that recommended by the statewide guideline may be appropriate, by describing the incidence of drug-resistant disease in our community. Data was collected on all episodes of pediatric pneumonia admitted to the Townsville Hospital between Jan 2009-Jun 2013. This cohort received a variety of antibiotics due to the previous lack of any protocol, and some were commenced by local specialists on broader treatment earlier in the course, while others received what has now become the suggestions in the statewide policy. The control group will be those who were successfully treated in accordance with, what is now, the statewide policy, to compare to those who received alternative options for either clinical reasons or practitioner choice.

Sponsors

Dr Nathan Smalley
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
0 to 16 Years
Healthy volunteers
No

Inclusion criteria

All children admitted to our hospital from the North Queensland region with pneumonia as their key diagnosis.

Exclusion criteria

Adult age.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026