Metal ion levels post primary unilateral Exeter total hip arthroplasty

Metal ion levels at 1 year post primary unilateral Exeter total hip arthroplasty

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613000787785

Enrollment

Registered

2013-07-15

Start date

2012-02-23

Completion date

2012-08-02

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Metal ion release is common following total hip arthroplasty, yet postoperative levels have not been defined for most stems currently used in clinical practice. The Exeter stem is the most commonly used cemented stem in Australia. The aim of this study is to assess metal ion release in the serum of patients with well functioning unilateral Exeter V40 primary total hip arthroplasties one year after surgery.

Interventions

metal ion levels at 1 year post total hip replacement

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

(1) one year post primary unilateral Exeter V40 total hip replacement (cemented femoral component with cemented or uncemented acetabular component), (2) no prosthesis or metalwork elsewhere, (3) Harris Hip Score > 80 and no signs/symptoms of infection, (4) no radiographical signs of loosening, (5) no significant systemic diseases affecting metal metabolism (including chronic renal failure with eGFR < 30) and (6) no chronic exposure to metal ions (eg occupational)

Exclusion criteria

(1) more than one joint replaced (2) harris hip score <=80 (3) signs or symptoms of infection (4) loosening on x-ray (5)presence of systemic diseases known to affect metal metabolism (6) chronic exposure to metal ions

Outcome results