None listed
Conditions
Brief summary
Patients having operations under general anaesthesia will be asleep for the duration of the procedure and their own breathing efforts will be reduced by the anaesthetic drugs. The anaesthetist will support the patients breathing and will place a breathing tube into his/her windpipe as soon as the patient have drifted off to sleep. Normally, the anaesthetist discontinues the administration of oxygen during this manoeuvre as it usually takes only a short time to insert the breathing tube. We believe that continuing the supply of oxygen through a small tube into the inside of the patients cheek at this stage will keep the body oxygen levels higher than they would be otherwise. This is especially important for patients who are overweight or pregnant and also in children as their oxygen reserves exhaust more quickly. Computer programs and our understanding of the biology of people have suggested this would be the case. However, we do not have proof of this at present.
Interventions
In theatre patients will receive a standardised induction of anesthesia . For the the laryngoscopy (procedure to visualise the vocal cords and therefore entrance into the windpipe) and intubation (placement of the endotracheal tube into the windpipe) in the anaesthetised and apnoeic patient, the oxygen administration is traditionally interrupted for a short time until the breathing tube is connected to the ventilator. In this study the patients are either receiving additional oxygen (10 l/min fl
In theatre patients will receive a standardised induction of anesthesia . For the the laryngoscopy (procedure to visualise the vocal cords and therefore entrance into the windpipe) and intubation (placement of the endotracheal tube into the windpipe) in the anaesthetised and apnoeic patient, the oxygen administration is traditionally interrupted for a short time until the breathing tube is connected to the ventilator. In this study the patients are either receiving additional oxygen (10 l/min flow) via a 3.5 mm RAE tube in the buccal space during laryngascopy or no additional oxygen. During artificially prolonged laryngoscopy the saturation will be recorded for a maximum of 10 min or until the saturation starts to drop to 95%. The patient will then be intubated and anaesthesia will be continued as per routine.
Sponsors
Department of Anaesthesia, Royal Perth Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1) Adult patients requiring general anaesthesia with endotrachel intubation for scheduled surgery 2) BMI 30-40 3) ASA1-2 4) Agree to and capapble of understanding and signing the consent form
Exclusion criteria
Study population - Exclusion criteria: 1) Age < 18 2) Chronic Respiratory Disease 3 ) SpO2 <98% despite preoxygenation with 100% O2 4) History of difficult intubation or anticipated difficult intubation 5) Uncontrolled hypertension 6) Ischaemic Heart disease or congestive Heart Failure 7) Increased intracranial pressure 7) Gastroesophageal reflux disease 8) Non fasting patients 9) Emergency procedures
Outcome results
None listed