ANZ 1301 (DOMINO): Exploring decision making about neoadjuvant chemotherapy for operable breast cancer.

ANZ 1301 (DOMINO): Women who have had a diagnosis of invasive breast cancer in the last 5 years and were offered or discussed neoadjuvant chemotherapy as a treatment option, will participate in a telephone questionnaire to identify factors influencing their decisions about neoadjuvant chemotherapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12613000658718

Acronym

DOMINO

Enrollment

Registered

2013-06-17

Start date

2013-07-29

Completion date

2013-08-26

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study aims to identify relevant issues and information needs of women who have considered or have had neoadjuvant chemotherapy treatment within the last five years for initially operable cancer, and incorporate them into a prospective questionnaire and decision aid for women diagnosed with operable breast cancer considering neoadjuvant chemotherapy. Who is it for? You may be eligible to join this study if you are aged over 18 years, have had a diagnosis of invasive breast cancer in the last 5 years, have been offered or have discussed neoadjuvant chemotherapy as a treatment option and have completed a surgical intervention for breast cancer. Trial details Participants in this study will be interviewed once over the phone to identify the issues faced and their prevalence and impact on decision making, and the level of distress associated with treatment for women who have considered or have had neoadjuvant chemotherapy treatment within the last five years for initially operable breast cancer. The findings will be incorporated into a prospective questionnaire and subsequent decision aid for women considering neoadjuvant chemotherapy for operable breast cancer.

Interventions

Telephone questionnaire. Each participant will do the questionnaire once. The questionnaire will take approximately 30 minutes. The first few questions are to check that the interview is right for the participant. The next questions are for general information on age, location (postcode only) and some general information about health insurance and where the participant was treated (public or private hospital). The rest of the questions will ask about: * Breast cancer diagnosis * What things the particpant thought about, or might think about, to help them decide whether or not to have chemotherapy before breast cancer surgery * What treatments the participant had for their breast cancer * What were their worries and concerns while they were having treatment for breast cancer * What information women should have, before deciding whether or not to have chemotherapy before breast cancer surgery. Some questions will have different answers to choose from and others also allow for comments to be made. Ten to twenty interviews will be conducted to identify the majority of relevant issues. The aim is for issue saturation, where no major new issues are raised in three consecutive interviews.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1) Participants must be female, >=18 years 2) Participants have had a diagnosis of invasive breast cancer in the last 5 years 3) Participants have been offered, or have discussed, neoadjuvant chemotherapy as a treatment option 4) Participants have completed surgical intervention for breast cancer 5) Participants are capable of giving informed consent

Exclusion criteria

1) Hearing or other impairment that would preclude a phone interview 2) Insufficient English language skills for participation

Outcome results