None listed
Conditions
Brief summary
In a 6 month dietary intervention trial, we aim to investigate the effects of an Australianised Mediterranean Diet on cognitive functioning, cardiovascular health and wellbeing in an elderly Australian free-living population. We will assess memory, executive functioning, verbal fluency and speed and accuracy, psychological well-being, weight, changes in body composition, blood lipids, blood pressure, inflammatory markers, blood glucose and insulin, and vascular endothelial function. We expect to find that an Australianised Mediterranean diet will show greater improvements in these outcomes when compared to a habitual diet.
Interventions
An Australianised Mediterranean Diet (MedDiet) based on the traditional Cretan Mediterranean diet, providing 100% of energy requirements for weight maintenance for 6 months in an elderly population (age 65 years or older). The MedDiet will consist of a high intake of vegetables, legumes, fruits, virgin olive oil, non-refined bread and cereal products and nuts; a moderate intake of low fat dairy products and lean poultry; a low intake of red meat, added sugar, salt and saturated fat, and moderate intake of red wine (if alcohol is habitually consumed) according to the NHMRC guidelines (2 drinks or less per day). The diet will aim to provide 35-40% energy from fat with >50% coming from monounsaturated fat, 15% energy from lean protein and 40-45% energy from carbohydrate. This should achieve a ratio of monounsaturated to saturated fat of 2. Physical activity will remain unchanged throughout the trial. This is a 6 month study and volunteers will undergo outcome assessments at baseline and again at 3 and 6 months. Each assessment timepoint will be conducted over 2 mornings (approx. 2hrs in duration) separated by a week.
Sponsors
Study design
Eligibility
Inclusion criteria
Male and females aged 65 years or more, proficient in English language, omnivorous, DemTect score 13 or over, free of dementia, non-smoker
Exclusion criteria
Subjects who report one or more of the following: history of head/brain injury, neurological or psychiatric conditions, previous stroke, using medication for neurological or psychiatric conditions, current or recent (past 6 months) malignancy, major liver, kidney, respiratory, gastrointestinal disease, current cardiovascular disease or angina, uncontrolled hypertension (>170/100), actively undertaking a weight loss program, use of appetite suppressants or Orlistat, participation in another dietary intervention study within 30 days of commencement of the present study, smoker, or any person considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol.