ultrasound guided transversus abdominis plane block versus local wound infiltration for post-operative analgesia in children undergoing appendectomy: A Randomized Controlled Trial

Status

Not yet recruiting

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000595718

Enrollment

Registered

2013-05-27

Start date

2013-06-01

Completion date

2013-07-01

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Appendectomy is one of the most frequently performed surgical procedures in children and is associated with significant postoperative discomfort and pain.Multimodal approaches to the provision of postoperative analgesia often incorporate blockade of the abdominal wall, such as ilioinguinal blockade or wound infiltration. However, the efficacy of these approaches is unclear. This study is a prospective,randomized comparison of 2 patient groups. One group of patients will receive an ultrasound guided transversus abdominis plane (TAP) block using 0.4 ml/kg of bupivacaine 0.25% with 1:200 000 epinephrine The total dose of bupivacaine will not exceed 2 mg/kg and the total volume will not be more than 20 ml. . The second group will receive local anesthetic infiltration by the surgeon at the end of surgery for a laparoscopic appendectomy.

Interventions

This study is a prospective,randomized comparison of 2 patient groups. One group of patients will receive an ultrasound guided transversus abdominis plane (TAP) block at the end of the surgery using 0.4 ml/kg of bupivacaine 0.25% with 1:200 000 epinephrine The total dose of bupivacaine will not exceed 2 mg/kg and the total volume will not be more than 20 ml.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

4 Years to 14 Years

Healthy volunteers

Inclusion criteria

- American Society of Anesthesiologists (ASA) classification score 1-2 - Age :4 year to14years -Weight less than or equal to 60 kg -Presenting for laparoscopic appendectomy

Exclusion criteria

- ASA physical status > II - Patients < 4 years of age - Weight greater than 60 kg - Co-morbid diseases (cardiac, pulmonary (not including asthma), neurological disease. - children undergoing an additional surgical procedure at an anatomical location not covered by a unilateral TAP block during the same anesthetic - children in whom a TAP block is contraindicated, i.e. surgical scar or distorted anatomy at the site of injection

Outcome results