Effects of a traditional Persian medicine syrup (Jollab) on Functional Dyspepsia patients

Survey on a traditional Iranian medicine syrup (Jollab) in relieving gastrointestinal symptoms in Functional Dyspepsia (FD) patients: a randomized double-blind placebo-controlled clinical trial

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000584730

Enrollment

150

Registered

2013-05-24

Start date

2013-06-01

Completion date

2013-10-16

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Functional Dyspepsia (FD) is a widespread disease in community. The pathophysiology of Fd is not clearly evident, yet. The disease has a huge expense for health system and the treatments aren't sufficient unfortunately. Traditional Persian Medicine originated from the knowledge of great physicians like Avicenna, presented herbal drugs which have been used by people for hundreds years. An inexpensive accessible Persian herbal syrup named as Jollab has been introduced in Traditional Persian Medicine books repeatedly. The aim of this study is to evaluate the efficacy of Jollab in relieveing symptoms of FD.

Interventions

A traditional Persian medicine syrup named Jollab, is administered orally 3 times daily, 45 milliliters totally, during 4 weeks. this syrup is a combination of distilled water, Rose water, Saffron and Sugar as mentioned in Avicenna's book (Al-Qanoon fil-teb). As the active agents have synergistic effect, there isn't way to specify the active ingredients amount. In order to monitor adherence, patient should check a form and render this form in follow-up meetings.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

1- Functional Dyspepsia (FD) patients according to Rome III criteria, based on general exam and gastrointestinal endoscopy 2- Normal range of lab data (CBC, LFT, Stool exam)

Exclusion criteria

1- Steatorrhoea 2- Celiac disease 3- Night Diarrhea 4- Beginning of FD after the age of 40 years 5- Cancer (any form) 6- Liver disease 7- Pulmonary disease 8- Auto-immune disease 9- Psychiatry disease 10- pregnancy 11- Lactation 12- Irritable Bowl Syndrome (IBS) 13- History of Abdominal Surgery 14- Treatment with Lactolose or similar drugs 15- Consumption of drugs contributed to FD simultaneously 16- Consumption of Analgesic or Narcotic drugs

Outcome results