None listed
Conditions
Brief summary
Pruritus is one of the most bothersome symptoms in patients on maintenance hemodialysis (HD), however little progress is seen in our understanding of its pathogenesis. The percentage of HD patients suffering from pruritus reportedly is higher than 50%. The aim of this study is to evaluate the frequency of pruritus in HD patients and to correlate its presence and intensity with relevant clinical and laboratory parameters.
Interventions
Patients on Hemodialysis more than 3 months will be asked regarding any complaining of pruritus and if present then detail history and examination regarding the pruritus(like character, distribution, scar mark, itching mark, xerosis present or not, etc) and it's any relation with laboratory parameters (like haemoglobin, haematocrit, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, reticulocytes, iron, ferritin, transferrin, transferrin saturation
Patients on Hemodialysis more than 3 months will be asked regarding any complaining of pruritus and if present then detail history and examination regarding the pruritus(like character, distribution, scar mark, itching mark, xerosis present or not, etc) and it's any relation with laboratory parameters (like haemoglobin, haematocrit, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, reticulocytes, iron, ferritin, transferrin, transferrin saturation, urea, creatinine, calcium, phosphorus, albumin, total protein, PTH, Alkaline Phosphatase and glucose.) Approximate duration of the examination 1-2 hour.
Sponsors
Dr Bappaditya Mondal
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
- age 18 year and more. - on maintenance HD attending HD units for more than 3 month - Patients who are able to understand and complete questionnaires
Exclusion criteria
- Patients who have pruritus attributed to causes other than chronic kidney disease (CKD) - Patients who have had significant alteration in their dialysis regimen within the 2 weeks prior to Screening (or those for whom such changes are anticipated during the study) are excluded. A "significant alteration" is defined as: A change in the type of hemodialysis filter; An increase or decrease in total duration of dialysis prescribed of > 1 hour/week; A change in the site or type of venous access for dialysis; An increase or decrease in prescribed blood flow of >100 mL/min; Patients who are unwilling to comply with the study protocol.
Outcome results
None listed