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In patients having key-hole surgery for appendicitis, does it matter if we use a thorough washout of the contaminated area or just suck out the contamination? This is a study to compare the rates of post-operative infection with the two methods.

In patients undergoing laparoscopic appendicectomy, does the use of suction-only as compared to irrigation-and-suction lead to a decrease in intra-abdominal infections?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12613000468729
Enrollment
140
Registered
2013-04-24
Start date
2013-06-03
Completion date
2013-12-31
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Laparoscopic appendicectomy is one of the most commonly performed urgent abdominal operations. Current practices of Irrigation or Suction-only are largely determined by individual surgeon’s bias based on intra-operative findings. To date, there is only one randomized, controlled trial comparing irrigation with suction only in children and none in adults. There is some retrospective data in children and adults. All of the existing data suggests “no difference” between these operative methods; in fact, some retrospective data suggest higher intra-abdominal abscess rates in irrigation groups, however there has never been a randomized trial in adults. There remains clinical equipoise and current practice is widely varied. Our hypothesis is that there is no difference between the two surgical methods and we aim to demonstrate that it doesn't matter to the patient which method is used.

Interventions

During laparoscopic appendicectomy, irrigator-suction catheters will be used which irrigate the surgical field with normal saline prior to suction.

Sponsors

Prof Steven Chan
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Adult patients (over 16) in whom appendicectomy is completed laparoscopically and the suppuration is localised to the right iliac fossa, right paracolic gutter or pelvis

Exclusion criteria

Appendicectomy for normal appendix or non-purulent appendicitis. Interval appendicectomy. Appendicectomy following percutaneous drainage of abscess.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026