Wrist acupressure for post-operative nausea and vomiting: A feasibility study

Wrist acupressure for post-operative nausea and vomiting: a comparison of PC 6 acupoint stimulation versus placebo for reducing postoperative nausea and vomiting in cardiac surgery patients (WRAP Trial)

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000416796

Acronym

WRAP

Enrollment

Registered

2013-04-15

Start date

2013-11-20

Completion date

2014-06-05

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Post-operative nausea and vomiting (PONV) are unwanted complications following anaesthesia and surgery. The occurrence of PONV ranges from 20% to 80%, despite optimal pharmacologic interventions. The burden of caring for patients post cardiac surgery in healthcare system world-wide is immense. In 2009-2010, In Australia alone, over 230,000 cardiac procedures were performed, and the number and rate of cardiac procedures are increasing. Similar to many countries world-wide, cardiovascular disease (CVD) remains the most expensive disease group in Australia, costing about $5.9 billion in 2004–05 with just over half of this money spent on patients admitted to hospital. As part of their illness treatment and recovery, cardiac surgery patients experience varying rates of PONV; studies across various populations have reported rates ranging from 22% to 50%.

Interventions

The PC6 acupoint is the meridian point in the pericardium channel and located on the inner forearm between the extensor carpi radialis and palmaris longus tendons one sixth of the distance from PC7 on the medial wrist crease to PC 3 in the cubital fossa (WHO, 2008). Participants in the intervention group (acupressure wristband) will have the Seaband (Registered Trademark) wristbands applied to both wrists ensuring the bead stimulates the Neiguan (PC 6) after establishment of IV access and invasive monitoring in the operating theatre. The wristbands will be covered with opaque bandaging to ensure blinding. The wristbands will be removed at 36 hours from admission time to ICU after final outcome measurement.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

- Elective and urgent primary cardiac surgery (CABG; valve and double valve replacement; CABG + single valve replacement - Able to understand, speak, read and write English - Over 18 years of age and able to give informed consent

Exclusion criteria

Add in wrist circumference>21cm.

Outcome results