None listed
Conditions
Brief summary
Double-blind randomized placebo controlled trial of children with persistant rhinitis, allergic to dust mites were included. All evaluationwas done at baseline and 12 months after randomisation as for clinical status, bronchial and nasal hyper-reactivity.
Interventions
Subjects were randomized to receive active sublingual immunotherapy or placebo using a double-blind method. Active Sublingual immunotherapy containing 300 Index of Reactivity/mL of Dermatophagoides pteronyssinus and Dermatophagoides farinae 50:50% or placebo. Both active sublingual immunotherapy and placebo were administered sublingually with 8 drops/once a day 3 times a week, for a 12 months treatment duration.
Sponsors
Marmara University medical faculty
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
5 Years to 10 Years
Healthy volunteers
No
Inclusion criteria
Children aged between 5-10 years of both genders with the history of persistent allergic rhinitis without asthmatic symptoms.
Exclusion criteria
Allergic asthma, previous allergen immunotherapy, chronic disease, malignancy.
Outcome results
None listed