A comparison of pre-emptive sciatic nerve block and post-amputation sciatic nerve block and their effect on the incidence of phantom limb pain post-operatively

For patients receiving below knee amputations comparing pre-emptive sciatic nerve blocks and post-amputation sciatic nerve blocks and their effect on the incidence of phantom limb pain post-operatively

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000227796

Enrollment

Registered

2013-02-26

Start date

2013-08-26

Completion date

2020-03-23

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Phantom limb pain after amputation is common and can be severe. This study will investigate whether blocking (anaesthetising) the patients sciatic nerve prior to having a below knee amputation will reduce the risk and or the severity of phantom limb pain.

Interventions

Pre-operative placement of sciatic nerve block (30ml of 0.25% bupivacaone) and catheter prior to commencement of below knee amputation. Local anaesthetic (3-5mL/hour 0.5% Bupivicaine) will continue to be infused continuously via the catheter for five days post-operatively (i.e. the infusion will continue around the clock).

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients having a Below Knee Amputation ASA 1 - 4

Exclusion criteria

Patient refusal Allergy to Local Anaesthetic Severe dementia Inability to complete questionnaire Inability to consent

Outcome results