Skip to content

Improving medication adherence in patients with chronic diseases

Targeted and tailored interventions to improve medication adherence compared to standard care in patients with chronic diseases

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12613000162718
Enrollment
120
Registered
2013-02-11
Start date
2013-03-25
Completion date
2014-02-10
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of the study is to identify patients with poor medication-taking behaviour and implement personalised interventions to improve medication-taking behaviour. We hope to learn about changes in medication-taking behaviour over time and to determine the degree to which improvements in this behaviour are sustained. We also want to learn if using the MAQ and Beliefs about Medicines Questionnaire - Specific was helpful to improve medication-taking behaviour. We hypothesise that: - Personalising interventions to patients known to have poor medication-taking behaviour will improve medication-taking behaviour at three months. - Improvements in medication-taking behaviour at three months will not be sustained at six months. - Medication-taking behaviour, and the reasons for poor medication-taking behaviour, will change over time in all groups studied.

Interventions

Interventions to improve medication adherence tailored to the identified patient reasons for non-adherence. These interventions may include implementing dose administration aids, telephone reminders, health coaching or motivational interviewing. The selected intervention will depend on the patient's reasons for non-adherence. Dose administration aids as an intervention will be implemented by explaining to the patient what a dose administration aid looks like and how it works, which will take

Interventions to improve medication adherence tailored to the identified patient reasons for non-adherence. These interventions may include implementing dose administration aids, telephone reminders, health coaching or motivational interviewing. The selected intervention will depend on the patient's reasons for non-adherence. Dose administration aids as an intervention will be implemented by explaining to the patient what a dose administration aid looks like and how it works, which will take approximately 10 minutes. If the patient agrees the patient will be referred onto the pharmacy to initiate dose administration aids for this patient. The pharmacy will create a medication profile for the patient by liaising with the patient's general practitioner. The patient's prescriptions will be kept by the pharmacy and dispensed. Dose administration aids will be packed on a fortnightly basis and patients will pick up the packs as needed. (This is the standard procedure of dose administration aids in a pharmacy and the delivery of these packs will be the responsibility of the pharmacy). From the researcher's own experience in packing dose administration aids, the initiation of the dose administration aid will take several hours. Telephone reminders will be implemented by initiating fortnightly phone calls discussing medication-taking behaviour after baseline. Health coaching or motivational interviewing will involve setting goals of medication-taking behaviour, which will be conducted at baseline and 3 and 6 months if appropriate. This will be facilitated in the private counselling area of the pharmacy and will involve a 20 minute one-on-one interview with the researcher (who is also a pharmacist). These interventions will be implemented at baseline and if necessary 3 and 6 months after baseline. The interventions will be implemented over the total trial duration of 6 months.

Sponsors

The University of Queensland
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- Patients attending one of the study pharmacies - Patients over 18 years of age - Diagnosed with at least one of the following chronic diseases: hypertension, type 2 diabetes, dyslipidaemia or cardiovascular disease - Patients taking a medication for one of the above chronic diseases from the following drug groups: ACE-inhibitors, calcium channel blockers, beta-blockers, oral hypoglycaemic drugs, lipid lowering agents - Patients with a newly initiated medication (from above) within the previous four to twelve weeks - Consent to participate in the study

Exclusion criteria

- Patients who do not adequately understand the study information (in the opinion of the researcher)

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 28, 2026