A comparison of alcohol delamination and phototherapeutic keratectomy for the treatment of recurrent erosion syndrome.

A comparative clinical trial of alcohol delamination versus phototherapeutic keratectomy for the treatment of recurrent corneal erosions.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000151730

Enrollment

Registered

2013-02-08

Start date

2007-02-06

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To compare two different treatment methods of reducing pain and recurrent episodes in individuals with recurrent corneal erosion syndrome, a syndrome characterised by pain, watering and light sensitivity due to episisodic loosening of the surface cells of the eye. The two methods are laser treatment and alcohol treatment to the surface of the eye. It is hypothesised that the two methods are comparable in their effect.

Interventions

alcohol delamination (removal of corneal epithelium with 50um of 25% ethyl alcohol for 40 seconds)

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject)

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

Individuals with symptomatic recurrent corneal erosion syndrome not responding to conservative treatment including regular topical lubrication and a bandage contact lens

Exclusion criteria

Individuals with a history of previous ocular surgery including any interventional treatment for their recurrent erosion syndrome other than manual epithelial debridement, prior herpetic eye disease, history of other corneal or external eye disease, corneal hypoaesthesia,or a history of diabetes mellitus

Outcome results