None listed
Conditions
Brief summary
Recently, data from observational (AusDiab) and experimental (IDLE breaks study) research indicates people who break up their sitting time throughout the day with light-intensity activity (such as light walking) may have better blood glucose and blood fat levels than people who sit for prolonged periods without activity breaks. This experimental study will examine the acute effect of prolonged sitting with and without light intensity activity bouts on memory functions (long-term and short-term memory and executive functions) in adults. Nineteen sedentary overweight/obese adults aged between 45-75 years will be recruited to attend two separate trial days interspersed by a one week washout period: control condition (sitting – 7 hours), a similar duration of sitting but with 3 minute light intensity activity bouts every 30 minutes. Cognitive testing, measurements of neurotrophic, metabolic, inflammatory, cortisol and catecholamine markers will be conducted. The proposed study will provide initial insights into whether breaking up sitting time with intermittent light-intensity activity has the potential for cognitive benefits whilst also describing the acute cognitive effects of prolonged sitting.
Interventions
This randomised crossover trial involves two single-day treatment conditions separated by a one week wash/out period. Intervention: Sitting + light-intensity activity bouts: Following an initial steady-state period (150 mins – initial 2 hours + 30 mins) of being seated, participants will complete a 3 min bout of light-intensity walking on the treadmill (level, firm surface, slow pace – 3.2 km/hr). They will then return to the seated position. This procedure will be repeated on another 9 occasion
This randomised crossover trial involves two single-day treatment conditions separated by a one week wash/out period. Intervention: Sitting + light-intensity activity bouts: Following an initial steady-state period (150 mins – initial 2 hours + 30 mins) of being seated, participants will complete a 3 min bout of light-intensity walking on the treadmill (level, firm surface, slow pace – 3.2 km/hr). They will then return to the seated position. This procedure will be repeated on another 9 occasions every 30 minutes. Total duration and intensity of activity: 30 minutes at light-intensity.
Sponsors
Baker IDI Heart and Diabetes Institute
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Inclusion criteria includes: overweight or obesity (body mass index (BMI) > 25 kg/m2, but < 40 kg/m2) and English-speaking.
Exclusion criteria
Exclusion is based on: pregnancy; employment in a non-sedentary occupation; currently watching < 3 hours of television per day; regularly engaged in moderate-intensity exercise = 150 min/week (‘sufficiently active’) for > 3 months; diabetes; use of lipid-lowering medication; known physical activity contraindications, major illness/injury (acute or chronic), cognitive or physical problems that may limit the ability to perform the necessary activity.
Outcome results
None listed