None listed
Conditions
Brief summary
This studies aims to compare blood vessel elasticity after two protein-rich meals which are high in either olive oil or palmolein (further purified fraction of palm oil). The study also aims to compare the effect of these test meals on blood markers of heart health.
Interventions
Participants will attend the clinic at 2 times points for approximately 6 hour visit, with a 1 week wash out period between treatments. They will be asked to eat a meal, which will be comprised of ‘regular’ foods (chicken, bread and salad) plus 40g of either palmolein oil or control oil, offered in a randomised order. they will have 15 minutes to consume the meal. the meals will contain 30% energy from protein, 58% energy from fat and 11% energy from carbohydrate. total energy content of the
Participants will attend the clinic at 2 times points for approximately 6 hour visit, with a 1 week wash out period between treatments. They will be asked to eat a meal, which will be comprised of ‘regular’ foods (chicken, bread and salad) plus 40g of either palmolein oil or control oil, offered in a randomised order. they will have 15 minutes to consume the meal. the meals will contain 30% energy from protein, 58% energy from fat and 11% energy from carbohydrate. total energy content of the test meals is ~2800kJ.
Sponsors
CSIRO Animal, Food and Health Sciences
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Male Age 18-65 years BMI: 25-35 kg/m2 and weight stable over the previous 3 months.
Exclusion criteria
Smoker (known to affect flow mediated dilatation - primary outcome) History of heavy alcohol consumption (> 5 STD drinks/day) Volunteer unable to limit alcohol consumption for study duration Type 1 or Type 2 diabetes Existing conditions that affect study outcomes, including kidney, respiratory, gastrointestinal, cardiovascular or peripheral vascular disease. Use of nitrate medication, non-steroidal anti-inflammtory medication or medication or supplements that may affect gastrointestinal function (such as antibiotics, laxatives etc) during the 3 months prior to study – or which are known to affect the outcomes of interest.
Outcome results
None listed