The anaesthesia pre-oxygenation trial - using O2 Flush and Nasal oxygen for pre-oxygenation compared to traditional methods.

The effect of anaesthesia pre-oxygenation with O2 flush and nasal prongs on end tidal O2 in healthy adult volunteers

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000126718

Enrollment

Registered

2013-02-01

Start date

2013-01-10

Completion date

2013-05-10

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Prior to general anaesthesia the standard of care is to pre-oxygenation all patients. This involves the patient breathing 100% oxygen via a face mask. The 3 most common methods of pre oxygenation involve 4 deep breaths over 30 seconds, 8 deep breaths over 60 seconds or 3 minutes of tidal volume breathing (normal breathing) using high flow 100% oxygen (15L per minute via the anaesthesia machine with a face mask). The most common reasons for poor preoxygenation is an inadequate face mask seal resulting in the patient breathing room air (low oxygen content) through the leak. Nasal oxygen and the anaesthesia machine oxygen flush delivery higher flow rates than the standard method by the the anaesthesia machine so may reduce the amount of inspired air from the leak. Study Hypothesis - High flow oxygen with nasal oxygen or anaesthesia machine oxygen flush produces higher end tidal oxygen levels (better pre oxygenation) in the simulated mask leak scenario.

Interventions

Each participants will perform repeated pre oxygenation in a computer generated randomised fashion. With a good mask seal 1. Standard - Anaesthesia machine (15L/min) 2. Standard PLUS nasal prong oxygenation 3. Standard PLUS anaesthesia machine oxygen flush With simulated face mask leak 4. Standard 5. Standard PLUS nasal prong oxygenation 6. Standard PLUS anaesthesia machine oxygen flush Each of these interventions will be assess using deep breathing for 90 seconds and tidal breathing for

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Investigator)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1. Age 18 and over 2. Healthy volunteers

Exclusion criteria

1. Refusal or withdrawal of consent at any stage 2. Pregnancy

Outcome results