None listed
Conditions
Brief summary
The main aim of this study is to assess the ability of a new test to detect endometrial cancer in post-menopausal women. The diagnostic test being evaluated involves performing a wash of the uterus and collecting this wash fluid for analysis of markers that are shed from cancer cells. Two different laboratory testing methods will be used to obtain information that will enable us to develop a more cost-effective, sensitive and specific test for detecting early stages of endometrial cancer. Who is it for? This studyis open to peri- and post-menopausal women aged 45-80 years with endometrial cancer and who are currently undergoing a hystrectomy procedure. Trial details In this study you will undergo a uterine wash procedure while under general anesthetic prior to hysterectomy procedure. The wash sample is then tested for specific MMPs.
Interventions
Participants admitted for treatment for endometrial cancer (usually involving a hysterectomy) undergo a uterine wash during the gynaecological procedure. The wash, which will take less than 5 minutes to collect, will contain enzymes called matrix metalloproteinases (MMPS), which are released into the uterine cavity in patients with endometrial cancer. Uterine washes will be transported to a test laboratory to be analysed for MMP levels using standard lab techniques. This testing will take a fe
Participants admitted for treatment for endometrial cancer (usually involving a hysterectomy) undergo a uterine wash during the gynaecological procedure. The wash, which will take less than 5 minutes to collect, will contain enzymes called matrix metalloproteinases (MMPS), which are released into the uterine cavity in patients with endometrial cancer. Uterine washes will be transported to a test laboratory to be analysed for MMP levels using standard lab techniques. This testing will take a few hours to complete.
Sponsors
Diagnotech Pty Ltd
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Investigator)
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Peri-menopausal and post-menopausal women with endometrial cancer that are undergoing a hysterectomy procedure
Exclusion criteria
- Men - Women who do not have endometiral cancer who do not fit the age range - Women who are not already having non-cancer gynecological treatment
Outcome results
None listed