Effective dose of remifentanil for control of hemodynamic response to insertion of the Streamlined Liner of the Pharyngeal Airway(SLIPA)

What is effective dose of remifentanil to control hemodynamic response to insertion of the Streamlined Liner of the Pharyngeal Airway(SLIPA)

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12613000086763

Enrollment

100

Registered

2013-01-23

Start date

2011-01-03

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A single administration of remifentanil can effectively suppress hemodynamic changes due to the insertion of Streamlined Liner of the Pharyngeal Airway. What is the Effective dose of remifentanil needed to suppress hemodynamic response from Streamlined Liner of the Pharyngeal Airway insertion?

Interventions

Before insertion of SLIPA, remifentanil (0.5microg/kg, 1.0microg/kg, 1.5microg/kg, 2.0microg/kg ) is injected. there are 4 different intervention groups who receive their allocated dose once only. remifentanil is injected intravenously.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used) (Caregiver)

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

Patients with healthy and aged 20-65 years old, who were planned general anesthesia.

Exclusion criteria

cardiovascular or pulmonary disease, reflux esophagitis, obesity (BMI > 30 kg/m²), or were pregnant, or were addicted to opioids, sedatives, or other medications

Outcome results